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Up Close - Women's Health - January 13, 2011
Heeding genetic red flags for breast-cancer risk
Doctors here say simple test can identify mutation carriers

By Chey Scott
Of the Journal of Business

Dr. Deborah Martinez, right, with patient Penny Browne, says not enough of the at-risk population is being tested for the BRCA1 and BRCA2 genetic mutations.
Dr. Deborah Martinez, right, with patient Penny Browne, says not enough of the at-risk population is being tested for the BRCA1 and BRCA2 genetic mutations.
—Staff photo by Chey Scott
For a woman whose family has a history of breast or ovarian cancer, a simple test can tell whether or not she's at a higher than average risk of developing cancer in her lifetime, based on her heredity, physicians here say.

In the early 1990s, two gene mutations were discovered and isolated by researchers at the Creighton University School of Medicine's Hereditary Cancer Center, in Omaha, Nebraska, that since have been linked to cancer. Women who have one of those two mutations, k...


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